In an interview with the "Bild", a German tabloid, Low revealed that he would no longer call-up Thomas Muller, Jerome Boateng and Mats Hummels as the team looks to build for the future and give the German national team a "new face".
"The young national players will have the space they need to fully develop, and now they have to take responsibility."
"The coach's sudden decision obviously left me puzzled".
"They will continue to do so for their club".
"2019 is a new beginning for the Germany national team", he said.
It was announced on Tuesday that Low will no longer select the Bayern Munich trio for Germany after the 2014 World Cup winners failed to make it past the group stages of the 2018 tournament in Russian Federation and then finished bottom of their Nations League group.
"As a matter of principle, we do not comment on the sporting decisions of the national coach as the selection of the national team squad is exclusively the responsibility of Joachim Low", the statement read.
"Thomas, Mats and Jerome have achieved a lot until now for German football", added Germany team manager Oliver Bierhoff.
And, DFB president Reinhard Grindel also spoke out on the decision, declaring: "I appreciate that Joachim wants to carry on changing the shape of the national side".
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In a statement, the two men described the move as part of a larger effort to make the Korean peninsula free from nuclear weapons. He said Kim demanded all sanctions on North Korea end at once in exchange for closing down the Yongbyon nuclear facility .
All three play for Bayern Munich and were part of the 2014 World Cup winning team but have now had their global careers seemingly ended by Low.
"We were surprised that this happened as part of an unannounced visit at (Bayern training complex) Saebener Strasse", said Rummenigge and Salihamidzic.
Hummels and Boateng, Germany's successful centre-back partnership before the disaster at the finals in Russian Federation, have played in 70 and 76 internationals respectively.
'I have no understanding for the suggested definitiveness of this decision.
Mueller, 29, has scored 10 goals at World Cups, winning the golden boot in 2010.
"I am sad about this news because it has always been the greatest thing for me to represent my country". I was always proud to wear the jersey, I've given everything, I want to thank you for your support, it was an incredible journey'. I was once young myself and depended on older players making room for me.
The 59-year-old Germany boss has been under pressure to make sweeping changes since his side crashed out of the 2018 World Cup in the first round.
Thomas Muller says he is angry about the way Joachim Low dumped him from the Germany squad. Even so, I would have liked a different farewell for us, of course.