From then Barca have played 28 games at home, 26 wins and two draws.
Barcelona could rest some of their most influential players against Tottenham next month, given they have already topped the group, but Pochettino said: "I don't know [what they'll do]. In the Champions League no one is going to give a present and not care about the result".
"When people say something is going to be hard I am so excited to show it is possible to do".
Mauricio Pochettino has said Juan Foyth's absence from Tottenham's Champions League squad list underlines the club's mistakes in the summer transfer window and their need to recruit homegrown talent.
"We have big respect for Barcelona, one of the best teams in Europe".
"It's so painful. It's a mistake that we made that at this level of football we can not repeat again".
"The form we're in right now, it's probably the flawless time to go there", he said."It's a game the fans want to win and one we want to win".
Eriksen's late show keeps Spurs in hunt for last 16 berth
"I think the performance was very good, we fully deserved the victory", said Pochettino.
Defeats in Italy and at home to Barcelona to begin their Champions League group have left the Londoners up against it in order to qualify for the knockout stages of the competition, and to have any chance of progressing they must win when the San Siro side head to London.
"We need to approach the game in the best way and believe that we can win".
"Hopefully, PSV will play the game with passion and desire, which will make things hard for Inter".
The Gunners are now on an 18-game unbeaten run under the stewardship of Unai Emery and have already sealed their progress to the next round of the Europa League.
Pochettino's side will go out if they fail to beat the Italian side at Wembley. "We need to change like basketball so players can go in and out". There aren't players who can play in all 12. "The most important thing is to try to avoid risk, mix the team with different players and rotate so all players feel important".
Melania Trump skips unveiling of White House Christmas decorations
The sunny hallway is lined with two columns of pine trees that are solid red and lack decorations. They include an ornament emblazoned with the slogan for her child well-being campaign, Be Best.