Rae revealed previous year that she was diagnosed with bone cancer.
She first appeared as Edna Garrett on "Diff'rent Strokes" in 1978 before earning her own spinoff, "The Facts of Life", the following year.
Off-stage and off-screen, Charlotte's life was a rich mixture of joy and heartbreak that included a 25 year marriage to and creative partnership with legendary composer and music editor and supervisor, John Strausswith whom she had two sons, Andy Strauss (who died in 1999) and Larry Strauss with whom she wrote her memoir, The Facts of My Life, in 2015. Rae won a Prime Time Emmy Award nomination for the role in 1982. She made her television debut in 1954, guest-starring on a number of shows before landing a role in 1979 on "Diff'rent Strokes". "I'm not in any pain right now", she explained at the time.
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Actress Charlotte Rae, born Charlotte Rae Lubotsky, died Sunday at the age of 92, her representatives confirm. "I'm feeling so terrific and so glad to be above ground", Rae told People Magazine. She has 93 acting credits to her name, according to TMZ. Now I have to figure out if I want to go have treatment again or opt for life. Rae left the show in 1986 for health reasons, and though Cloris Leachman stepped in as Mrs. Garrett's sister, the show was canceled two years later. Mrs. Garrett was the house mother at an all-girls' boarding school, and helped the students through some of the toughest moments of their lives. "The Phil Silvers Show", "ER", and "Girl Meets World", among others. "I love you Char", Cohn, who played Natalie, posted on Instagram. "If you saw it, you remember her reaching for Treat Williams".
Rae had survived a bout with pancreatic cancer in 2009, having caught the disease early following the deaths of her mother, uncle and sister to the disease.